Methylating fingers
نویسندگان
چکیده
منابع مشابه
Genetic sensor for strong methylating compounds.
Methylating chemicals are common in industry and agriculture and are often toxic, partly due to their propensity to methylate DNA. The Escherichia coli Ada protein detects methylating compounds by sensing aberrant methyl adducts on the phosphoester backbone of DNA. We characterize this system as a genetic sensor and engineer it to lower the detection threshold. By overexpressing Ada from a plas...
متن کاملWebbed fingers.
W ebbing of the digits, or syndactyly, is not caused by the fingers sticking together in the womb; rather, it is caused by failure, during the sixth to eighth weeks of intrauterine life, of the usual longitudinal interdigital necrosis that normally separates the fingers. This " webbing " is the most common abnormality of the newborn hand. It happens either as an isolated anomaly or as part of a...
متن کاملTransfer RNA methylating activity of yeast mitochondria.
Mitochondria isolated from Saccharomyces cerevisiae and purified in Urografin or sucrose gradient contain tRNA methylating activity with specificities different from those of the cytoplasm. The main reaction product, using E.coli tRNA as methyl group acceptor, is N(2),-N(2)-dimethylguanine. The corresponding mitochondrial methylase is coded by nuclear DNA. A DNA methylating activity is also ass...
متن کاملCrystalline Saffman-Taylor Fingers
We study the existence and structure of steady-state ngers in two-dimensional solidiication, when the surface energy has a crystalline anisotropy so that the energy-minimizing Wull shape and hence the solid-liquid interface are polygons, and in the one-sided quasi-static limit so that the diiusion eld satisses Laplace's equation in the liquid. In a channel of nite width, this problem is the cry...
متن کاملNickel transfer by fingers.
We investigated fingers as a potential source of nickel transfer to the face in patients with allergic contact dermatitis to nickel and a history of facial dermatitis. Samples were collected from the fingers and cheeks of volunteers using the stripping method with standard adhesive tape, and nickel levels were quantified using mass spectrometry. Fingers and cheeks of individuals who had handled...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Structural & Molecular Biology
سال: 2012
ISSN: 1545-9993,1545-9985
DOI: 10.1038/nsmb.2226